The Bills are two-point favorites for the AFC showdown between the top two teams in the conference. While the betting odds are on Buffalo's side, history is on Chiefs quarterback Patrick Mahomes' side.

Patrick Mahomes has shined as an underdog throughout his career. Exploring key team trends, and betting lines for this matchup.

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Butker had to have a meniscus trim. While he's out, the Chiefs signed kicker Spencer Shrader off the Jets practice squad to replace him. Over the course of nine games this season, Butker is 18-of-20 on field goal kicks and 21-of-22 on extra points.

KANSAS CITY, Mo. (AP) - Chiefs kicker Harrison Butker had surgery to repair the meniscus in his left, non-kicking knee on Friday, though coach Andy Reid said following practice that the two-time defending Super Bowl champions hope to have him back later this season.

Injuries continue to pile up for the Kansas City Chiefs heading into their Week 11 matchup against the Buffalo Bills. On Thursday, it was revealed that the defending Super Bowl champions intend to place star kicker Harrison Butker on their injured reserve list.