BACKGROUND: Vascular aging is an important phenotype characterized by structural and geometric remodeling. Some individuals exhibit supernormal vascular aging, associated with improved cardiovascular ...

The era of predictive modeling enhanced with machine learning and artificial intelligence (AI) to aid clinical ...

BACKGROUND: Direct reprogramming of fibroblasts to cardiomyocytes is a potentially curative strategy for ischemic heart ...

BACKGROUND: Primary aldosteronism (PA), an overt form of renin-independent aldosterone production, leads to a disproportionately high rate of major adverse cardiovascular events (MACEs). Mounting ...

BACKGROUND: Fontan circulatory failure (FCF) is a chronic state in palliated single ventricle heart disease with high morbidity and mortality rates, including heart failure, multisystem end-organ ...

In the article by Otto et al, “2020 ACC/AHA Guideline for the Management of Patients With Valvular Heart Disease: A Report of the American College of Cardiology/American Heart Association Joint ...

Although it was observed centuries ago that intravenous injection of oil resulted in mechanical obstruction of small vessels, 1 the exact pathophysiology of fat embolism syndrome (FES) remains ...

There are continuous myths, fallacies, and debates about hypertension, its treatment, risk factor status, and especially treatment targets. This is most regrettable, because hypertension is a silent ...

A 12-year-old, apparently healthy woman was referred to the echocardiography laboratory as part of evaluation of school physical control. Physical examination was unremarkable. Two-dimensional ...

There are several potential mechanisms for the favorable effects of omega-3 fatty acids on overall cardiovascular health (Table 1). Omega-3 fatty acids lower triglyceride levels and increase ...

In 1975, Tuttle and Mills 1 published in Circulation Research an article entitled “Dobutamine: development of a new catecholamine to selectively increase cardiac contractility.” This work, having been ...

Pericardial agenesis is a congenital heart defect frequently misdiagnosed due to lack of symptoms and clinical awareness. The aim of this case report is to describe the most common features associated ...